Mesacol CR 2gm Granules is an anti-inflammatory medicine used to treat a type of bowel disease known as ulcerative colitis. It helps to reduce symptoms such as diarrhea, bleeding and stomach pain by reducing inflammation in the bowel.Mesacol CR 2gm Granules may also be used to treat another type of bowel disease known as Crohn?s ileocolitis. It should be taken with food. The tablets should be swallowed whole with water, do not break, crush, or chew them. The dose will depend on what you are being treated for but take it exactly as your doctor prescribes. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen.